For a 27-year-old woman newly diagnosed with human papillomavirus genotype 16, what is the recommended next step in management?

The recommended next step in management for a 27-year-old woman newly diagnosed with human papillomavirus genotype 16 is cervical colposcopy. This is primarily due to the high-risk nature of HPV genotype 16, which is associated with a significant risk of developing cervical dysplasia and cervical cancer.

When a patient tests positive for a high-risk HPV type, especially in the age group where cervical screening is actively conducted, it is essential to evaluate the cervix for any precancerous lesions. Colposcopy allows for a detailed examination of cervical tissues and the opportunity to obtain biopsies of any abnormal areas detected. This procedure is critical because early detection and management of dysplastic changes can prevent the progression to cervical cancer.

In contrast, while Pap testing is important for routine cervical cancer screening, in the context of a known high-risk HPV type, colposcopy is preferred as the immediate next step. HPV vaccination can help prevent future infections but does not address the current diagnosis or potential existing pathology. Referral to oncology would only be necessary if significant lesions or cancer were diagnosed, which is not determined solely by HPV status. Therefore, colposcopy aligns directly with the goal of early intervention and management of potential cervical abnormalities.