In patients with chronic lymphocytic leukemia, what laboratory finding is typical?

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In patients with chronic lymphocytic leukemia (CLL), a high lymphocyte count is a characteristic laboratory finding. CLL is a type of cancer that primarily affects the bone marrow and blood, leading to the accumulation of abnormal lymphocytes, which are a subtype of white blood cells crucial for the immune response.

The disease often presents with an elevated peripheral blood lymphocyte count that can be significantly higher than normal. As CLL progresses, it can lead to symptoms such as lymphadenopathy and splenomegaly due to the infiltration of lymphoid tissue by these malignant cells. The increase in lymphocytes is a hallmark of the disease and helps differentiate it from other forms of leukemia and hematologic disorders.

Understanding this laboratory finding is essential for diagnosing CLL and monitoring its progression or response to treatment.

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