Which regions of the esophagus are commonly affected by medication-induced esophagitis?

Medication-induced esophagitis is primarily associated with the proximal and distal segments of the esophagus. This occurs because specific medications can become lodged in the esophagus, particularly in areas where the lumen is narrower, such as the proximal esophagus and the distal esophagus near the lower esophageal sphincter.

The proximal esophagus is at risk due to swallowing dynamics and anatomical factors that can lead to medication retention, while the distal esophagus may also be affected due to similar retention and the acidity of gastric contents which can exacerbate esophageal irritation. Therefore, these two regions are the most commonly implicated in cases of medication-induced esophagitis. Recognizing the regions involved allows for better prevention and management strategies in patients who are at risk of this condition due to their medication regimens.